|
Main
Cluster
|
Pattern |
GO
Name |
GO |
Changed |
Measured |
in
GO |
Z
Score |
P
Value |
| 1 |
Early
induction |
|
|
|
|
|
|
|
|
T-helper
1 type immune response |
P |
4 |
9 |
10 |
6.44 |
<0.001 |
|
|
regulation
of metabolism |
P |
8 |
41 |
48 |
5.34 |
<0.001 |
|
|
G2/M
transition of mitotic cell cycle |
P |
3 |
8 |
8 |
5.04 |
0.001 |
|
|
nucleus |
C |
97 |
1804 |
2790 |
4.10 |
<0.001 |
|
|
endoplasmic
reticulum |
C |
23 |
293 |
335 |
3.77 |
0.001 |
|
|
regulation
of cell cycle |
P |
18 |
212 |
258 |
3.69 |
<0.001 |
|
|
circadian
rhythm |
P |
3 |
13 |
23 |
3.68 |
0.006 |
|
|
ubiquitin
ligase complex |
C |
3 |
13 |
15 |
3.68 |
0.01 |
|
|
nucleosome
assembly |
P |
4 |
22 |
36 |
3.58 |
0.01 |
|
|
protein
transporter activity |
F |
15 |
178 |
227 |
3.33 |
0.005 |
|
|
Golgi
apparatus |
C |
18 |
230 |
288 |
3.31 |
0.002 |
|
|
transcription |
P |
59 |
1075 |
1359 |
3.22 |
0.002 |
|
|
phosphoric
monoester hydrolase activity |
F |
11 |
126 |
165 |
2.97 |
0.009 |
|
|
intracellular
transport |
P |
23 |
346 |
460 |
2.91 |
0.008 |
|
|
transcription
regulator activity |
F |
41 |
728 |
898 |
2.81 |
0.004 |
|
|
transition
metal ion homeostasis |
P |
3 |
19 |
19 |
2.77 |
0.03 |
|
|
nucleosome |
C |
3 |
19 |
38 |
2.77 |
0.037 |
|
|
RAS
small monomeric GTPase activity |
F |
3 |
20 |
21 |
2.66 |
0.038 |
|
|
nucleic
acid binding |
F |
77 |
1581 |
2068 |
2.61 |
0.008 |
|
|
kinase
activity |
F |
30 |
512 |
675 |
2.60 |
0.012 |
|
|
protein
binding |
F |
62 |
1235 |
1646 |
2.56 |
0.014 |
|
|
heart
development |
P |
4 |
33 |
45 |
2.54 |
0.036 |
|
|
cellular_component
unknown |
C |
24 |
393 |
780 |
2.53 |
0.016 |
|
|
endomembrane
system |
C |
8 |
92 |
101 |
2.52 |
0.026 |
|
|
protein
amino acid dephosphorylation |
P |
7 |
77 |
99 |
2.49 |
0.03 |
|
|
ubiquitin-protein
ligase activity |
F |
4 |
35 |
47 |
2.40 |
0.034 |
|
|
hemopoiesis |
P |
5 |
52 |
60 |
2.24 |
0.048 |
|
|
intracellular
signaling cascade |
P |
25 |
443 |
567 |
2.17 |
0.038 |
|
|
cell
differentiation |
P |
12 |
177 |
208 |
2.15 |
0.048 |
|
|
microtubule
associated complex |
C |
5 |
55 |
90 |
2.10 |
0.044 |
| 2 |
Sustained
Induction |
|
|
|
|
|
|
|
|
protein
modification |
P |
67 |
595 |
747 |
4.81 |
<0.001 |
|
|
phosphotransferase
activity\, alcohol group as acceptor |
F |
49 |
401 |
512 |
4.70 |
<0.001 |
|
|
phosphorus
metabolism |
P |
51 |
441 |
548 |
4.37 |
<0.001 |
|
|
endomembrane
system |
C |
16 |
92 |
101 |
4.23 |
<0.001 |
|
|
cytoplasm |
C |
168 |
2040 |
2532 |
3.50 |
<0.001 |
|
|
hematopoietin/interferon-class
(D200-domain) cytokine receptor activity |
F |
9 |
49 |
54 |
3.35 |
0.005 |
|
|
small
protein conjugating enzyme activity |
F |
5 |
21 |
31 |
3.20 |
0.017 |
|
|
actin
filament-based process |
P |
9 |
52 |
62 |
3.15 |
0.004 |
|
|
cellular_component
unknown |
C |
40 |
393 |
780 |
2.97 |
0.004 |
|
|
protein
binding |
F |
104 |
1235 |
1646 |
2.86 |
0.006 |
|
|
biological_process
unknown |
P |
43 |
439 |
804 |
2.82 |
0.006 |
|
|
intracellular
transport |
P |
35 |
346 |
460 |
2.74 |
0.008 |
|
|
cell
projection organization and biogenesis |
P |
3 |
12 |
13 |
2.59 |
0.04 |
|
|
morphogenesis
of an epithelium |
P |
4 |
19 |
22 |
2.56 |
0.034 |
|
|
ubiquitin-protein
ligase activity |
F |
6 |
35 |
47 |
2.54 |
0.034 |
|
|
RAS
small monomeric GTPase activity |
F |
4 |
20 |
21 |
2.43 |
0.038 |
|
|
response
to biotic stimulus |
P |
41 |
439 |
941 |
2.42 |
0.022 |
|
|
regulation
of cellular process |
P |
19 |
172 |
201 |
2.41 |
0.022 |
|
|
phosphoric
ester hydrolase activity |
F |
18 |
162 |
213 |
2.37 |
0.025 |
|
|
purine
nucleotide binding |
F |
78 |
933 |
1171 |
2.36 |
0.021 |
|
|
intracellular
signaling cascade |
P |
41 |
443 |
567 |
2.36 |
0.018 |
| 3 |
Late
induction |
|
|
|
|
|
|
|
|
lysosome |
C |
22 |
73 |
89 |
8.12 |
<0.001 |
|
|
nucleoside
kinase activity |
F |
4 |
8 |
9 |
4.94 |
<0.001 |
|
|
chromatin
remodeling |
P |
5 |
12 |
20 |
4.89 |
0.001 |
|
|
chromatin
silencing complex |
C |
3 |
5 |
7 |
4.80 |
0.001 |
|
|
immune
cell homeostasis |
P |
4 |
9 |
9 |
4.57 |
0.001 |
|
|
antigen
processing\, endogenous antigen via MHC class I |
P |
3 |
6 |
8 |
4.28 |
0.012 |
|
|
MHC
class I receptor activity |
F |
3 |
6 |
10 |
4.28 |
0.012 |
|
|
antigen
presentation |
P |
6 |
20 |
29 |
4.21 |
0.001 |
|
|
membrane
lipid metabolism |
P |
10 |
48 |
62 |
3.97 |
0.001 |
|
|
immune
cell chemotaxis |
P |
4 |
11 |
14 |
3.97 |
0.004 |
|
|
integral
to membrane |
C |
196 |
2360 |
3419 |
3.85 |
<0.001 |
|
|
regulation
of endocytosis |
P |
5 |
17 |
20 |
3.78 |
0.003 |
|
|
immunoglobulin
binding |
F |
3 |
9 |
9 |
3.23 |
0.017 |
|
|
protein
amino acid dephosphorylation |
P |
12 |
77 |
99 |
3.18 |
0.002 |
|
|
lipid
kinase activity |
F |
4 |
16 |
17 |
2.96 |
0.017 |
|
|
regulation
of gene expression\, epigenetic |
P |
6 |
30 |
37 |
2.95 |
0.014 |
|
|
cytoskeletal
protein binding |
F |
21 |
177 |
206 |
2.84 |
0.009 |
|
|
alcohol
dehydrogenase activity |
F |
3 |
11 |
15 |
2.76 |
0.031 |
|
|
GTPase
regulator activity |
F |
16 |
127 |
161 |
2.73 |
0.009 |
|
|
receptor
signaling protein activity |
F |
10 |
68 |
84 |
2.69 |
0.011 |
|
|
intracellular
signaling cascade |
P |
43 |
443 |
567 |
2.68 |
0.012 |
|
|
lymph
gland development |
P |
4 |
18 |
25 |
2.67 |
0.022 |
|
|
hydrolase
activity |
F |
103 |
1238 |
1642 |
2.60 |
0.007 |
|
|
zinc
ion binding |
F |
18 |
154 |
188 |
2.55 |
0.011 |
|
|
negative
regulation of transcription\, DNA-dependent |
P |
8 |
52 |
60 |
2.55 |
0.021 |
|
|
cell
death |
P |
26 |
245 |
290 |
2.55 |
0.008 |
|
|
carbohydrate
metabolism |
P |
23 |
211 |
272 |
2.53 |
0.014 |
|
|
transcriptional
repressor activity |
F |
6 |
36 |
41 |
2.43 |
0.032 |
|
|
inositol/phosphatidylinositol
kinase activity |
F |
4 |
20 |
23 |
2.41 |
0.045 |
|
|
external
side of plasma membrane |
C |
5 |
30 |
49 |
2.22 |
0.048 |
|
|
endosome |
C |
5 |
31 |
38 |
2.13 |
0.048 |
|
|
integrin-mediated
signaling pathway |
P |
6 |
41 |
51 |
2.07 |
|