Protein Tyrosine Kinase ZAP-70

MGI MGI:99613

Expression Profile

  MGI  SwissProt  PhenOntology  Affy  Unigene  RefSeq  LocusLink  GeneOntology  

MGI  Top

ID: MGI:99613
Symbol: Zap70
Name: zeta-chain (TCR) associated protein kinase

SwissProt  Top

ID: P97455
Accession: P97455
Name: ZAP70
Species: Mus musculus
Protein: Tyrosine kinase.
ID: ZA70_MOUSE
Accession: P43404
Name: ZAP70
Species: Mus musculus
Protein: Tyrosine-protein kinase ZAP-70 (EC 2.7.1.112) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).
Functions: Associates with the T-cell antigen receptor zeta chain (CD3Z). Plays a role in lymphocyte activation.

PhenOntology  Top

ID: MP:0000716
Name: immune system: cellular abnormalities
ID: MP:0000716
Name: immune system: cellular abnormalities
ID: MP:0001790
Name: immune system: response/function abnormalities
ID: MP:0002113
Name: skeletal: osteogenesis/developmental anomalies

Affy  Top

ID: 1422701_at
ID: 1439749_at
ID: 1440178_x_at
ID: 93661_at
ID: 93662_s_at
ID: 93663_r_at
ID: Msa.282.0_s_at
ID: Msa.35370.0_s_at

Unigene  Top

ID: Mm.8038
Title: zeta-chain (TCR) associated protein kinase
Gene: Zap70
Cytoband: 1 20.5 cM

RefSeq  Top

ID: NM_009539

LocusLink  Top

ID: 22637
Symbol: Zap70
Name: zeta-chain (TCR) associated protein kinase

GeneOntology  Top

ID: 0004672
Name: protein kinase activity
ID: 0004674
Name: protein serine/threonine kinase activity
ID: 0004713
Name: protein tyrosine kinase activity
ID: 0005515
Name: protein binding
ID: 0005524
Name: ATP binding
ID: 0005829
Name: cytosol
ID: 0006468
Name: protein amino acid phosphorylation
ID: 0007242
Name: intracellular signaling cascade
ID: 0009887
Name: organogenesis
ID: 0016301
Name: kinase activity
ID: 0016740
Name: transferase activity

Remarks  Top

Expression Dataset (gene specific):
   Msa.282.0_s_at: NULL
   Msa.35370.0_s_at: NULL

Expression Profile  Top

Gene ID Msa.282.0_s_at Msa.35370.0_s_at
Quiescence-Term-18
HOPACH Clusters
Quiescence-Term-Post
Quiescence-Term-14
Quiescence-T-P 2fold
Postpartum
non-pregnant avg 111.8 675.06
14days avg 114.68 680.3
14days fold 1.03 1.01
16days avg 105.67 663.98
16days fold -1.06 -1.02
16v14 fold -1.09 -1.02
17days avg 107.06 667.22
17days fold -1.04 -1.01
17v16 fold 1.01 1
18days avg 107.15 634.4
18days fold -1.04 -1.06
18v14 fold -1.07 -1.07
18v16 fold 1.01 -1.05
18v17 fold 1 -1.05
6hrs avg 108.53 672.12
6hrs fold -1.03 -1
6v18 fold 1.01 1.06
24hrs avg 102.7 586
24hrs fold -1.09 -1.15
24v18 fold -1.04 -1.08
24v6 fold -1.06 -1.15
GenBank U04379 AA119473
GenMAPP ID P43404 P43404
Gene_Symbol Zap70 Zap70
MapLocation 1 20.5 cM 1 20.5 cM
f-rawp 0.0964 0.4983
f-adjp 1 1
gestation >20p 0 0
post>20p 0 0
gestation<-20p 0 0
post<-20p 0 0
Sum all 0 0
np fold-log 0 0
14d fold-log 0.04 0.01
16d fold-log -0.08 -0.02
17d fold-log -0.06 -0.02
18d fold-log -0.06 -0.09
6hrs fold-log -0.04 -0.01
24hrs fold-log -0.12 -0.2
final cluster NULL NULL
main cluster NULL NULL
2nd level cluster NULL NULL
main/medoid order NULL NULL
Mediod NULL NULL
total in cluster NULL NULL
final order NULL NULL
HOPACH Pattern NULL NULL
Abs-main cluster NULL NULL
Abs final order NULL NULL
Abs-Pattern NULL NULL
  Top